設施農業：綠能設施開發【材料系汪俊延教授】
論文篇名 英文：Novel dental resin composites containing LiAl-F layered double hydroxide (LDH) filler: Fluoride release/recharge, mechanical properties, color change, and cytotoxicity
中文：包含LiAl-F層狀雙氫氧化物（LDH）填料的新型牙科樹脂複合材料：氟化物釋放/補給，機械性能，顏色變化和細胞毒性
期刊名稱 Dental Materials
發表年份,卷數,起迄頁數 2019,35,663-672
作者 Liang Wei Su, Dan Jae Lin, Jun-Yen Uan★ (corresponding author)
DOI 10.1016/j.dental.2019.02.002
 
中文摘要 新型的具有有益的陰離子交換特性的LiAl-F層狀雙氫氧化物（LDH）被開髮用作氟化物儲層。本研究旨在研究含LDH的牙科樹脂複合材料的氟化物釋放/再填充能力及其對物理和生物學特性的影響。將3％和5％的LDH（R3，R5），濕磨的微型LDH（R3W，R5W）或乾磨的納米LDH（R3D，R5D）添加到微混合流動性樹脂複合材料（RX ）。選擇商業牙科用複合物（CC）進行比較。離子選擇性電極記錄了每天釋放的氟化物90天（每天從第30天到第60天再充電）。彎曲試驗根據ISO 4049進行。此外，評價了表面顯微硬度，顏色變化（L *，a *，b *），Al3 / Li 離子浸出和細胞毒性。包含LDH的樹脂複合材料的氟化物釋放和再充電能力顯著提高。其中，R3和R5具有比R3W，R5W，R3D，R5D和CC更穩定的長期氟釋放。儘管在第一天檢測到少量的Al3 / Li 離子，但LDH填充劑並未誘導細胞毒性。 LDH填料不會改變RX的彎曲強度，顯微硬度（R3，R5，R3D和R5D）顯著高於CC組（P <0.01）。 LDH填料略微增加了複合inred（a *值）和黃色（b *值）的顏色。
英文摘要 A novel LiAl-F layered double hydroxide (LDH) with a beneficial anions-exchangeable feature was developed for use as a fluoride reservoir. This study aims toinvestigate the fluoride release/ recharge capability of an LDH-contained dental resin com-posite and their effects on physical and biological properties.Methods. 3% and 5% of LDH (R3, R5), wet-milled micro-scale LDH (R3W, R5W), or dry-millednano-scale LDH (R3D, R5D) were added to a micro-hybrid flowable resin composite (RX). Acommercial dental compomer (CC) was selected for comparison. An ion selective electroderecorded the daily fluoride release for 90 days (Daily fluoride recharging from 30th to 60thday). The flexural tests were performed according to ISO 4049. Also, the surface microhard-ness, color changes (L*, a*, b*), Al3 /Li ion leaching, and cytotoxicity were evaluated.Results. The LDH-contained resin composites show significantly increased fluoride releaseand recharge capability. Among them, R3 and R5 have more stable and long-term fluoriderelease than R3W, R5W, R3D, R5D, and CC. The LDH filler did not induce cytotoxicity, althoughfew amounts of Al3 /Li ions were detected on the first day. The LDH filler did not alter theflexural strength of RX, and the microhardness (R3, R5, R3D, and R5D) was significantly higherthan the CC group (P < 0.01). The LDH filler slightly increased the color of the composite inred (a* values) and yellow (b* values).